⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783642 | 1.00 | — | — | |
| SCHEMBL21232047 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5784452 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31603446 | 0.97 | — | — | |
| SCHEMBL2916954 | 0.84 | — | — | |
| SCHEMBL10059315 | 0.82 | — | — | |
| SCHEMBL1401177 | 0.82 | — | — | |
| SCHEMBL588857 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL20520978 | 0.80 | GHSR (0.35) | — | |
| Hydrochloric Acid SCHEMBL1190877 | 0.80 | GHSR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076448-A1 | SOMATOSTATIN MODULATORS FOR TREATING PITUITARY ADENOMAS | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| EP-3317277-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2017003723-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2017-01-05 | — | — | WO | disclosed |