⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037966 | 1.00 | — | — | |
| SCHEMBL28466005 | 1.00 | — | — | |
| SCHEMBL19692708 | 0.83 | — | — | |
| SCHEMBL22158786 | 0.83 | — | — | |
| SCHEMBL22158785 | 0.83 | — | — | |
| SCHEMBL16045961 | 0.83 | — | — | |
| SCHEMBL21378368 | 0.83 | — | — | |
| SCHEMBL21378367 | 0.83 | — | — | |
| SCHEMBL16055022 | 0.83 | — | — | |
| SCHEMBL19700730 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778607-B1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2023-08-30 | — | — | EP | claimed |
| US-12630561-B2 | Tricyclic derivatives inhibitor, preparation method, and applications thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2026-05-19 | — | — | US | disclosed |
| US-12624050-B2 | Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2026-05-12 | — | — | US | disclosed |
| US-12583866-B2 | Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists | BEONE MEDICINES I GMBH (CH) | 2026-03-24 | — | — | US | disclosed |
| EP-4686476-A1 | PHOSPHOINOSITIDE 3 KINASE (PI3K) INHIBITOR FOR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | Klostermeier, Stefanie (DE) | 2026-02-04 | — | — | EP | disclosed |
| CN-120202205-A | Tri-ring PI3K alpha inhibitor, and preparation method and medical application thereof | 微境生物医药科技(上海)有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-111909173-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-118994200-A | Tri-ring PI3K alpha inhibitor, and preparation method and medical application thereof | 微境生物医药科技(上海)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-3805231-B1 | INHIBITOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD (CN) | 2024-10-16 | — | — | EP | disclosed |
| CN-113227101-B | Salt or crystal form containing tricyclic derivative and pharmaceutical composition thereof | 上海翰森生物医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| WO-2018109204-A1 | PROCESS FOR THE PREPARATION OF (S)-2-((2-((S)-4-(DIFLUOROMETHYL)-2-OXOOXAZOLIDIN-3-YL)-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)AMINO) PROPANAMIDE | F. HOFFMANN-LA ROCHE AG (CH) | 2018-06-21 | — | — | WO | disclosed |
| WO-2018109204-A1 | PROCESS FOR THE PREPARATION OF (S)-2-((2-((S)-4-(DIFLUOROMETHYL)-2-OXOOXAZOLIDIN-3-YL)-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)AMINO) PROPANAMIDE | F. HOFFMANN-LA ROCHE AG (CH) | 2018-06-21 | — | — | WO | disclosed |
| US-20180127404-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-20170210733-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-07-27 | — | — | US | disclosed |
| US-9650393-B2 | Benzoxazepin oxazolidinone compounds and methods of use | GENENTECH, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| US-9643980-B2 | Benzoxazepin oxazolidinone compounds and methods of use | GENENTECH, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20170015678-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-20170002022-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2017001645-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2017-01-05 | — | — | WO | disclosed |
| WO-2017001658-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2017-01-05 | — | — | WO | disclosed |