⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360702 | 1.00 | — | — | |
| SCHEMBL2037966 | 1.00 | — | — | |
| SCHEMBL19692708 | 0.83 | — | — | |
| SCHEMBL22158786 | 0.83 | — | — | |
| SCHEMBL22158785 | 0.83 | — | — | |
| SCHEMBL16045961 | 0.83 | — | — | |
| SCHEMBL21378368 | 0.83 | — | — | |
| SCHEMBL21378367 | 0.83 | — | — | |
| SCHEMBL16055022 | 0.83 | — | — | |
| SCHEMBL19700730 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909173-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112047960-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-112062778-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117377660-A | Process for the preparation of benzoxazepine oxazolidinone compounds | 基因泰克公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-109265408-B | Synthesis method of difluoromethyl substituted oxan-2-ketone | 上海皓元生物医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |