Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 13/20 | 0.74 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361822 | 0.92 | LOXL2 (0.74) | LOXL2PPARGPPARAPPARD | |
| SCHEMBL18361829 | 0.91 | LOXL2 (0.70) | LOXL2PPARGPPARAHTR2C | |
| Acetic Acid SCHEMBL20337848 | 0.90 | LOXL2 (0.67) | LOXL2PPARGPPARA | |
| Acetic Acid SCHEMBL20337861 | 0.90 | LOXL2 (0.66) | LOXL2PPARGPPARAHTR2CPPARD | |
| SCHEMBL18361824 | 0.87 | LOXL2 (0.64) | LOXL2HTR2C | |
| Trifluoroacetic Acid SCHEMBL20337918 | 0.86 | LOXL2 (0.67) | LOXL2PPARGPPARAPPARD | |
| SCHEMBL19952733 | 0.86 | LOXL2 (0.64) | LOXL2PPARGPPARA | |
| SCHEMBL18362031 | 0.85 | LOXL2 (1.00) | LOXL2 | |
| SCHEMBL20337919 | 0.85 | LOXL2 (0.66) | LOXL2PPARGPPARAPPARD | |
| SCHEMBL18361807 | 0.85 | LOXL2 (0.65) | LOXL2HTR2CMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017003862-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-01-05 | — | — | WO | disclosed |