SCHEMBL18364646

SCHEMBL18364646

Oc1ccc2cc(C(O)c3c[nH]c4ccccc34)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
GPR84 Q9NQS5 2/20 0.45
FFAR1 O14842 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MGAM O43451 4/20 0.44
GAA P10253 4/20 0.44
SI P14410 4/20 0.44
MGAM2 Q2M2H8 4/20 0.44
AHR P35869 1/20 0.44
NR3C1 P04150 1/20 0.43
PGR P06401 1/20 0.43
NR3C2 P08235 1/20 0.43
AR P10275 1/20 0.43
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18364666 0.85 HTR2A (0.48) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL21202506 0.82 MGAM (0.41) GPR84FFAR1MGAMGAASI
SCHEMBL18364658 0.81 MAPT (0.46) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL6379817 0.81 MAPT (0.56) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL13763231 0.77 MAPT (0.59) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL8213938 0.77 MAPT (0.67) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL18374989 0.76 CDK4 (0.52) MAPTMEN1KMT2ATDP1GAA
SCHEMBL29871427 0.75 MAPT (0.57) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL13763230 0.75 MGAM (0.58) MAPTGPR84FFAR1MEN1KMT2A
SCHEMBL28767073 0.75 MAPT (0.54) MAPTGPR84FFAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS MSMO1, NOM1, CD68 MAPT 293/4885GPR84 2980/4885FFAR1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.