SCHEMBL18364666

SCHEMBL18364666

CC(c1ccc2cc(O)ccc2c1)c1c[nH]c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
HTR2B P41595 1/20 0.48
GPR84 Q9NQS5 3/20 0.48
FFAR1 O14842 2/20 0.48
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NR3C1 P04150 1/20 0.45
PGR P06401 1/20 0.45
NR3C2 P08235 1/20 0.45
AR P10275 1/20 0.45
MGAM O43451 6/20 0.45
GAA P10253 6/20 0.45
SI P14410 6/20 0.45
MGAM2 Q2M2H8 6/20 0.45
CMA1 P23946 1/20 0.40
MC4R P32245 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18364646 0.85 MAPT (0.48) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL18364649 0.82 MEN1 (0.48) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL18364664 0.77 CDK4 (0.51) MEN1MAPTKMT2ATDP1GAA
SCHEMBL18364645 0.76 GPR84 (0.62) HTR2AHTR2CHTR2BGPR84FFAR1
Vibrindole A SCHEMBL5960513 0.75 GPR84 (0.71) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL29871427 0.74 MAPT (0.57) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL18364660 0.74 GPR84 (0.56) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL3495495 0.73 GUSB (0.61) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL29540078 0.73 GUSB (0.61) HTR2AHTR2CHTR2BGPR84FFAR1
SCHEMBL11020997 0.73 TYR (0.56) MEN1KMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS MSMO1, NOM1, CD68 HTR2A 2888/4885HTR2C 3373/4885HTR2B 2163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.