SCHEMBL18364672

SCHEMBL18364672

C=CC(=O)OCCOc1ccc(-c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.65
RAB9A P51151 4/20 0.58
THRB P10828 1/20 0.58
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
NPC1 O15118 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
KDM4E B2RXH2 2/20 0.44
RARB P10826 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 2/20 0.42
GAA P10253 1/20 0.42
KCNH2 Q12809 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13419207 0.96 MAPT (0.71) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL26329683 0.95 MAPT (0.58) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL12918678 0.93 MAPT (0.59) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL22507203 0.93 MAPT (0.56) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL12918664 0.92 MAPT (0.65) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL22369984 0.92 MAPT (0.65) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL21500180 0.92 MAPT (0.55) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL1105193 0.89 MAPT (0.64) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL12141874 0.89 MAPT (0.64) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL24805348 0.88 MAPT (0.62) MAPTRAB9ATHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007042-B2 Composition, light reflecting film, luminance-improving film, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2018-06-26 US disclosed
US-20170010398-A1 COMPOSITION, LIGHT REFLECTING FILM, LUMINANCE-IMPROVING FILM, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed
US-20170010398-A1 COMPOSITION, LIGHT REFLECTING FILM, LUMINANCE-IMPROVING FILM, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed