SCHEMBL26329683

SCHEMBL26329683

C=CC(=O)OCCOc1ccc(C(=O)Oc2ccc(-c3ccc(C(=O)OC)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
RAB9A P51151 2/20 0.53
THRB P10828 1/20 0.53
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
ACR P10323 3/20 0.43
HGFAC Q04756 1/20 0.43
PRSS1 P07477 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 2/20 0.41
NPC1 O15118 2/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21500180 0.96 MAPT (0.55) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL18364672 0.95 MAPT (0.65) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL26329681 0.93 THRB (0.53) MAPTRAB9ATHRBSMN1; SMN2ACR
SCHEMBL13419207 0.91 MAPT (0.71) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL13232820 0.90 THRB (0.53) MAPTRAB9ATHRBTDP1L3MBTL1
SCHEMBL23944799 0.90 THRB (0.56) MAPTRAB9ATHRBL3MBTL1SMN1; SMN2
SCHEMBL24804843 0.90 THRB (0.56) MAPTRAB9ATHRBL3MBTL1SMN1; SMN2
SCHEMBL17301210 0.90 THRB (0.56) MAPTTHRBTDP1L3MBTL1SMN1; SMN2
SCHEMBL23943770 0.90 THRB (0.56) MAPTRAB9ATHRBL3MBTL1SMN1; SMN2
SCHEMBL13417874 0.90 MAPT (0.57) MAPTRAB9ATHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241403-A1 POLARIZER AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-07-18 US disclosed
US-11822180-B2 Polarizer and image display device FUJIFILM CORPORATION (JP) 2023-11-21 US disclosed
US-11768323-B2 Polarizer and image display device FUJIFILM CORPORATION (JP) 2023-09-26 US disclosed