SCHEMBL183687

SCHEMBL183687

CN1C[C@H](C(=O)O)C=C2c3cccc4[nH]cc(c34)C[C@H]21

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.80
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
MAPT P10636 2/20 0.80
RECQL P46063 2/20 0.80
USP2 O75604 1/20 0.80
PLEC Q15149 1/20 0.80
DRD2 P14416 5/20 0.74
DRD3 P35462 5/20 0.74
HTR2B P41595 5/20 0.74
HTR6 P50406 5/20 0.74
HTR2A P28223 5/20 0.74
HTR1A P08908 4/20 0.74
DRD4 P21917 4/20 0.74
DRD5 P21918 4/20 0.74
HTR1D P28221 4/20 0.74
HTR1E P28566 4/20 0.74
HTR7 P34969 4/20 0.74
HRH1 P35367 4/20 0.74
HTR5A P47898 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473364 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL1371966 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL11533855 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL1162252 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL12951376 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
Water SCHEMBL11245600 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Ammonia Solution, Strong SCHEMBL5792359 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Ammonia Solution, Strong SCHEMBL26970704 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Hydrochloric Acid SCHEMBL31443171 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Acetamide SCHEMBL29094036 0.96 KDM4E (0.74) KDM4EMEN1KMT2AMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5367 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629555-B2 Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same PERIMETER SOLUTIONS, LP (US) 2026-05-19 US claimed
CN-122028945-A Apparatus, systems, and methods for aerosolized drug administration GH研究爱尔兰有限公司 2026-05-12 CN claimed
WO-2026043908-A1 COMPOSITIONS AND METHODS TO IMPROVE SEQUESTRATION OF MYCOTOXINS AND THEIR USE IN DETOXIFICATION OF ANIMAL FEED AND ANIMAL PRODUCTION SYSTEMS ALLTECH, INC. (US) 2026-02-26 WO claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
US-20250360150-A1 METHODS OF USING NEUROPLASTIC AGENTS AND TERRAFORMING MARS BRANNOCK METCALF MOLLY CAROLINE (US) 2025-11-27 US claimed
US-20250339483-A1 EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON INTRANASAL ADMINISTRATION, AND USES THEREOF AGS THERAPEUTICS SAS (FR) 2025-11-06 US claimed
EP-4642780-A2 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED HYDROLYSIS OF BROMOCRIPTINE Ceruvia Lifesciences LLC (US) 2025-11-05 EP claimed
US-20250304573-A1 LYSERGIC ACID DERIVATIVES AND METHODS UNIV FLORIDA STATE RES FOUND INC (US) 2025-10-02 US claimed
EP-0072286-B1 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1986-10-29 EP claimed
US-4524208-A Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1985-06-18 US claimed
US-4491664-A Process for the production of ergot alkaloids SANDOZ LTD. (CH) 1985-01-01 US claimed
EP-0095092-A2 Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1983-11-30 EP claimed
EP-0029082-B1 1-BENZYLATED ERGOMETRINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM VEB Arzneimittelwerk Dresden (DD) 1983-04-20 EP claimed
EP-0072286-A1 Organic amide compounds derived from nitrogenous lipids FIDIA S.p.A. (IT) 1983-02-16 EP claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed
EP-0000533-B1 N-SUBSTITUTED 9,10-DIHYDROLYSERGIC ACID ESTERS AND A METHOD FOR THEIR PREPARATION LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (YU) 1981-08-05 EP claimed
US-4230859-A Process for the preparation of N-substituted esters of 9,10-dihydrolysergicacids LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) 1980-10-28 US claimed
US-4145549-A CYCLIZATION, SOLVOLYSIS SANDOZ LTD. (CH) 1979-03-20 US claimed