SCHEMBL1371966

SCHEMBL1371966

CN1C[C@@H](C(=O)O)C=C2c3cccc4[nH]cc(c34)C[C@H]21

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.80
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
MAPT P10636 2/20 0.80
RECQL P46063 2/20 0.80
USP2 O75604 1/20 0.80
PLEC Q15149 1/20 0.80
DRD2 P14416 5/20 0.74
DRD3 P35462 5/20 0.74
HTR2B P41595 5/20 0.74
HTR6 P50406 5/20 0.74
HTR2A P28223 5/20 0.74
HTR1A P08908 4/20 0.74
DRD4 P21917 4/20 0.74
DRD5 P21918 4/20 0.74
HTR1D P28221 4/20 0.74
HTR1E P28566 4/20 0.74
HTR7 P34969 4/20 0.74
HRH1 P35367 4/20 0.74
HTR5A P47898 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473364 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL11533855 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL1162252 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL12951376 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL183687 1.00 KDM4E (0.80) KDM4EMEN1KMT2AMAPTRECQL
Water SCHEMBL11245600 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Ammonia Solution, Strong SCHEMBL5792359 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Ammonia Solution, Strong SCHEMBL26970704 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Hydrochloric Acid SCHEMBL31443171 0.99 KDM4E (0.79) KDM4EMEN1KMT2AMAPTRECQL
Acetamide SCHEMBL29094036 0.96 KDM4E (0.74) KDM4EMEN1KMT2AMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
EP-4642780-A2 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED HYDROLYSIS OF BROMOCRIPTINE Ceruvia Lifesciences LLC (US) 2025-11-05 EP claimed
CN-118956995-B Method for producing lysergic acid by fermentation 扬州联澳生物医药有限公司 2025-04-22 CN claimed
US-20240287057-A1 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED HYDROLYSIS OF BROMOCRIPTINE CERUVIA LIFESCIENCES LLC (US) 2024-08-29 US claimed
US-20240228479-A1 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED BROMINATION OF LYSERGIC ACID CERUVIA LIFESCIENCES LLC (US) 2024-07-11 US claimed
WO-2024145604-A2 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED HYDROLYSIS OF BROMOCRIPTINE CERUVIA LIFESCIENCES LLC (US) 2024-07-04 WO claimed
WO-2024145546-A1 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED BROMINATION OF LYSERGIC ACID CERUVIA LIFESCIENCES LLC (US) 2024-07-04 WO claimed
CN-116024107-B Engineering bacterium for producing lysergic acid, construction method and application thereof 中国科学院青岛生物能源与过程研究所 2023-10-03 CN claimed
CN-116024107-A Engineering bacterium for producing lysergic acid, construction method and application thereof 中国科学院青岛生物能源与过程研究所 2023-04-28 CN claimed
CN-1956985-A Process for the manufacture of lysergic acid IVAX PHARMACEUTICALS SRO (CZ) 2007-05-02 CN claimed
EP-1718644-A1 PROCESS FOR THE MANUFACTURE OF LYSERGIC ACID IVAX Pharmaceuticals s.r.o. (CZ) 2006-11-08 EP claimed
WO-2005082902-A1 PROCESS FOR THE MANUFACTURE OF LYSERGIC ACID IVAX PHARMACEUTICALS S.R.O. (CZ) 2005-09-09 WO claimed
EP-0072286-B2 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1992-12-09 EP claimed
EP-0205068-B1 LYSERGIC-ACID AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM ARZNEIMITTELWERK DRESDEN GmbH (DE) 1992-01-02 EP claimed
EP-0095092-B1 PROCESS FOR THE PREPARATION OF LYSERGIC ACID ESTERS SCHERING AKTIENGESELLSCHAFT (DE) 1986-12-30 EP claimed
EP-0072286-B1 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1986-10-29 EP claimed
US-4524208-A Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1985-06-18 US claimed
EP-0095092-A2 Process for the preparation of lysergic acid esters SCHERING AKTIENGESELLSCHAFT (DE) 1983-11-30 EP claimed
EP-0072286-A1 Organic amide compounds derived from nitrogenous lipids FIDIA S.p.A. (IT) 1983-02-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287057-A1 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED HYDROLYSIS OF BROMOCRIPTINE LIPA, CEL, LIPE KDM4E 944/4885MEN1 2600/4885KMT2A 101/4885
US-20240228479-A1 PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED BROMINATION OF LYSERGIC ACID LIPA, NAAA, BRS3 KDM4E 1037/4885MEN1 3530/4885KMT2A 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.