Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.60 |
| ▸ | MAPK7 | Q13164 | 12/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.45 |
| ▸ | DCLK1 | O15075 | 6/20 | 0.45 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.44 |
| ▸ | DCLK2 | Q8N568 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18369822 | 0.92 | MAPK7 (0.65) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369933 | 0.91 | BRD4 (0.61) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369897 | 0.89 | BRD4 (0.65) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369915 | 0.88 | BRD4 (0.64) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369882 | 0.88 | BRD4 (0.60) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369935 | 0.86 | BRD4 (0.69) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369930 | 0.86 | BRD4 (0.61) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369872 | 0.85 | BRD4 (0.64) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369937 | 0.85 | BRD4 (0.60) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18370048 | 0.85 | MAPK7 (0.75) | BRD4MAPK7KCNH2LRRK2DCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | BRD4 4/4885MAPK7 58/4885KCNH2 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.