Methacrylic Acid

Methacrylic Acid

SCHEMBL1837039

C(OCC1CO1)C1CO1.C=C(C)C(=O)O.C=C(C)C(=O)OCC(C)(C)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2584025 0.96 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1TP53CYP3A4
Methacrylic Acid SCHEMBL18037940 0.83 TSHR (0.41) ALDH1A1TSHRTHRB
Methacrylic Acid SCHEMBL27937976 0.82 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TP53CYP3A4
Methacrylic Acid SCHEMBL27476394 0.82 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TP53CYP3A4
Propylene Oxide SCHEMBL3757664 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTHRB
Methacrylic Acid SCHEMBL9005438 0.81 ALDH1A1 (0.62) ALDH1A1TSHRMAPK1TP53CYP3A4
Methacrylic Acid SCHEMBL3458430 0.81 TSHR (0.68) ALDH1A1TSHRMAPK1TP53CYP3A4
Methacrylic Acid SCHEMBL925804 0.81 TSHR (0.68) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL14816323 0.80 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL14633739 0.80 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-1834975-B1 Thermosetting poly(phenylene ether) SABIC INNOVATIVE PLASTICS IP (NL) 2011-05-11 EP claimed
EP-1834975-A1 Poly(Phenylene ether) - Polyvinyl thermosetting resin General Electric Company (US) 2007-09-19 EP claimed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US claimed
US-6352782-B1 None US disclosed
EP-1834975-B1 Thermosetting poly(phenylene ether) SABIC INNOVATIVE PLASTICS IP (NL) 2011-05-11 EP disclosed
EP-2316870-A1 Poly(phenylene ether) - polyvinyl thermosetting resin SABIC Innovative Plastics IP B.V. (NL) 2011-05-04 EP disclosed
EP-1834975-A1 Poly(Phenylene ether) - Polyvinyl thermosetting resin General Electric Company (US) 2007-09-19 EP disclosed
EP-1265946-B1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GEN ELECTRIC (US) 2007-03-28 EP disclosed
US-6617398-B2 Forming laminate; curing; cladding with copper; printed circuits GENERAL ELECTRIC COMPANY 2003-09-09 US disclosed
EP-1265946-A1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GENERAL ELECTRIC COMPANY (US) 2002-12-18 EP disclosed
US-20020028337-A1 Poly (phenylene ether) - polyvinyl thermosetting resin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-03-07 US disclosed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US disclosed
US-20010053450-A1 POLY (PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-12-20 US disclosed
WO-2001040354-A1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GENERAL ELECTRIC COMPANY (US) 2001-06-07 WO disclosed