Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 3/20 | 0.77 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.77 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.77 |
| ▸ | GJB2 | P29033 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SELL | P14151 | 2/20 | 0.49 |
| ▸ | SELP | P16109 | 2/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357280 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL13109610 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22067762 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL25005884 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22067763 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL23183598 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL21068067 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL23393554 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22431206 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL13242189 | 1.00 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540409-B2 | Synthetic amphiphiles for membrane protein manipulation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-01-10 | — | — | US | disclosed |