SCHEMBL183737

SCHEMBL183737

C=C(C)C(=O)OCc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 3/20 0.39
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP12 P39900 1/20 0.38
TDP1 Q9NUW8 3/20 0.34
MTOR P42345 1/20 0.34
RAB9A P51151 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204301 0.98 TSHR (0.45) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL18470685 0.91 TSHR (0.38) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL26363015 0.91 TSHR (0.40) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL10234474 0.88 TSHR (0.38) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL10262868 0.85 TSHR (0.39) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL12094947 0.85 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL15604062 0.85 TSHR (0.36) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL30985914 0.84 TSHR (0.33) TSHRTHRBALDH1A1MMP1MMP2
SCHEMBL3691321 0.83 MMP1 (0.44) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL5889433 0.82 MMP1 (0.39) MMP1MMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119674204-A Perfluorinated solid polymer electrolyte material and preparation method thereof 武汉理工大学 2025-03-21 CN claimed
CN-117756977-A Fluorine-containing acrylate copolymer, adhesive, protective film and application thereof 江苏皇冠新材料科技有限公司 2024-03-26 CN claimed
CN-117050224-A Preparation method of fluororubber raw rubber for lithium battery packaging 浙江巨圣氟化学有限公司 2023-11-14 CN claimed
CN-116444761-A Wear-resistant hydrolysis-resistant polyurethane elastomer material and processing technology thereof 盛鼎高新材料有限公司 2023-07-18 CN claimed
CN-115340622-A Polymer matrix fluorine-containing liquid chromatography column and preparation method thereof 济南化道新材料科技有限公司 2022-11-15 CN claimed
CN-114196279-B Low-surface-energy ship primer and preparation method thereof 浙江鱼童新材料股份有限公司 2022-07-29 CN claimed
CN-114196279-A Low-surface-energy ship primer and preparation method thereof 浙江鱼童新材料股份有限公司 2022-03-18 CN claimed
CN-111073467-B Corrosion-resistant composite protective layer material for neodymium iron boron 浙江中杭新材料科技有限公司 2021-08-06 CN claimed
CN-111073466-B Preparation method of low-cost high-corrosion-resistance neodymium iron boron 浙江中杭新材料科技有限公司 2021-04-30 CN claimed
CN-112646418-A Quantum dot ink, preparation method of quantum dot light-emitting diode and display device 广东聚华印刷显示技术有限公司 2021-04-13 CN claimed
EP-1376167-A1 Graded index type optical fibers Mitsubishi Rayon Co., Ltd. (JP) 2004-01-02 EP claimed
US-6529665-B1 Concentrically nonblended vinyl polymeric layers; small transmission loss; large numerical aperture; heat and moisture resistance; communications MITSUBISHI RAYON CO., LTD. 2003-03-04 US claimed
EP-1026525-A1 REFRACTIVE INDEX PROFILE TYPE OPTICAL FIBER Mitsubishi Rayon Co., Ltd. (JP) 2000-08-09 EP claimed
US-5684059-A FLUOROMONOMER, HYDROXYALKYL ACRYLATE OR METHACRYLATE, N-VINYL LACTAM, SULFONIC ACID MONOMER OPTIMERS, INC. 1997-11-04 US claimed
EP-0253515-B1 Fluorine containing soft contact lens hydrogels OPTIMERS INC (US) 1995-08-09 EP claimed
EP-0563047-A4 1994-02-09 EP claimed
EP-0563047-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE, Joseph C. (US) 1993-10-06 EP claimed
WO-1992011300-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE JOSEPH C (US) 1992-07-09 WO claimed
US-4990582-A Wettable, oxygen permeable resistant to protein deposits OPTIMERS, INC. 1991-02-05 US claimed
EP-0253515-A2 Fluorine containing soft contact lens hydrogels OPTIMERS INC. (US) 1988-01-20 EP claimed