Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 4/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375196 | 1.00 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL9391159 | 0.85 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL1803033 | 0.85 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL5721934 | 0.85 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL18494069 | 0.85 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL6423218 | 0.85 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL2782953 | 0.84 | MME (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL468451 | 0.84 | MME (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL468452 | 0.84 | MME (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Water SCHEMBL9506493 | 0.83 | EPHX1 (0.53) | EPHX1HPGDSALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017007695-A1 | MU OPIOID RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-12 | — | — | WO | disclosed |