Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.86 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.86 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18374527 | 0.92 | OPRM1 (1.00) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20369635 | 0.92 | OPRM1 (1.00) | OPRM1OPRK1OPRD1 | |
| SCHEMBL18374526 | 0.92 | OPRM1 (1.00) | OPRM1OPRK1OPRD1 | |
| SCHEMBL18375168 | 0.92 | OPRM1 (1.00) | OPRM1OPRK1OPRD1 | |
| SCHEMBL30072369 | 0.89 | OPRM1 (0.80) | OPRM1OPRK1OPRD1 | |
| SCHEMBL28915803 | 0.89 | OPRM1 (0.80) | OPRM1OPRK1OPRD1 | |
| SCHEMBL28915038 | 0.89 | OPRM1 (0.80) | OPRM1OPRK1OPRD1 | |
| SCHEMBL30072226 | 0.89 | OPRM1 (0.80) | OPRM1OPRK1OPRD1 | |
| SCHEMBL28915039 | 0.89 | OPRM1 (0.80) | OPRM1OPRK1OPRD1 | |
| SCHEMBL28905940 | 0.84 | OPRM1 (0.75) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017007695-A1 | MU OPIOID RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-12 | — | — | WO | disclosed |