Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 12/20 | 0.83 |
| ▸ | TLL1 | O43897 | 3/20 | 0.83 |
| ▸ | TLL2 | Q9Y6L7 | 3/20 | 0.83 |
| ▸ | MMP12 | P39900 | 5/20 | 0.71 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375804 | 0.94 | BMP1 (0.85) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL18255485 | 0.93 | BMP1 (0.88) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL21498503 | 0.92 | BMP1 (0.87) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL20586998 | 0.91 | BMP1 (1.00) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL16898049 | 0.91 | BMP1 (1.00) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL16898435 | 0.91 | BMP1 (1.00) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL18375782 | 0.90 | BMP1 (0.68) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL18255464 | 0.90 | BMP1 (0.89) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL18375450 | 0.89 | BMP1 (0.80) | BMP1TLL1TLL2MMP12C3AR1 | |
| SCHEMBL18375589 | 0.88 | BMP1 (0.79) | BMP1TLL1TLL2MMP12C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017006296-A1 | N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP1, TLL1 AND/OR TLL2 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-01-12 | — | — | WO | disclosed |