Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Risedronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 11/20 | 0.80 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.80 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Risedronic Acid SCHEMBL29380338 | 1.00 | FDPS (0.80) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL3953153 | 0.99 | FDPS (0.78) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL4755300 | 0.99 | FDPS (0.78) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL536966 | 0.99 | FDPS (0.78) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL5970387 | 0.99 | FDPS (0.78) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL29738088 | 0.99 | FDPS (0.78) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL4643040 | 0.99 | FDPS (0.83) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL5175755 | 0.91 | FDPS (0.80) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL5176322 | 0.91 | FDPS (0.70) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 | |
| Risedronic Acid SCHEMBL22720090 | 0.89 | FDPS (0.94) | FDPSBTN3A1PDE3ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9315 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236646-A1 | TRUNCATED VARICELLA-ZOSTER VIRUS ENVELOPE GLYCOPROTEIN GE | XIAMEN UNIVERSITY (CN) | 2025-07-24 | — | — | US | claimed |
| CN-120131676-A | Tablet containing risedronate sodium and application thereof | 天津市中西医结合医院（天津市南开医院） | 2025-06-13 | — | — | CN | claimed |
| CN-119385959-B | Risedronate sodium tablet and preparation method thereof | 山东第一医科大学附属省立医院(山东省立医院) | 2025-04-01 | — | — | CN | claimed |
| CN-119700711-A | Enteric nanoparticle preparation and preparation method thereof | 重庆医科大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119679734-A | Tablet containing risedronate sodium and rhizoma sparganii total flavonoids and application thereof | 山东新时代药业有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119385959-A | Risedronate sodium tablet and preparation method thereof | 山东第一医科大学附属省立医院(山东省立医院) | 2025-02-07 | — | — | CN | claimed |
| CN-119112759-A | Risedronate sodium-bletilla polysaccharide soluble microneedle and preparation method and application thereof | 贵州医科大学 | 2024-12-13 | — | — | CN | claimed |
| CN-119074907-A | Two-dimensional risedronate manganese nanobelt and preparation method and application thereof | 南京邮电大学 | 2024-12-06 | — | — | CN | claimed |
| US-20240390364-A1 | Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions | REID CHRISTOPHER BRIAN (US) | 2024-11-28 | — | — | US | claimed |
| CN-118986999-A | Application of nitrogen-containing bisphosphonate compound in preparation of anti-cryptosporidium tazii medicines | 河南农业大学 | 2024-11-22 | — | — | CN | claimed |
| WO-2003086355-A1 | NOVEL POLYMORPHS AND PSEUDOPOLYMORPHS OF RISEDRONATE SODIUM | TEVA PHARMACEUTICAL INDUDSTRIES, LTD. (IL) | 2003-10-23 | — | — | WO | claimed |
| US-20030195170-A1 | Novel polymorphs and pseudopolymorphs of risedronate sodium | TEVA PHARMACEUTICALS USA, INC. | 2003-10-16 | — | — | US | claimed |
| US-20030095945-A1 | Bone hemostasis method and materials | CHILDREN'S HOSPITAL LOS ANGELES | 2003-05-22 | — | — | US | claimed |
| EP-1307206-A2 | METHOD FOR ENHANCING BONE MINERAL DENSITY GAIN BY ADMINISTRATION OF RALOXIFENE | ELI LILLY AND COMPANY (US) | 2003-05-07 | — | — | EP | claimed |
| EP-1231869-A4 | BONE HEMOSTASIS METHOD AND MATERIALS | LOS ANGELES CHILDRENS HOSPITAL (US) | 2003-01-08 | — | — | EP | claimed |
| EP-1231869-A1 | BONE HEMOSTASIS METHOD AND MATERIALS | Children's Hospital of Los Angeles (US) | 2002-08-21 | — | — | EP | claimed |
| WO-2002024214-A2 | USE OF GLP -2 IN COMBINATION WITH ANOTHER THERAPEUTIC AGENT IN BONE-RELATED AND NUTRITION-RELATED DISORDERS | OSTEOMETER BIOTECH A/S (DK) | 2002-03-28 | — | — | WO | claimed |
| US-20020037836-A1 | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders | SANOS BIOSCIENCE A/S (DK) | 2002-03-28 | — | — | US | claimed |
| WO-2002007733-A2 | METHOD FOR ENHANCING BONE MINERAL DENSITY GAIN BY ADMINISTRATION OF RALOXIFENE | ELI LILLY AND COMPANY (US) | 2002-01-31 | — | — | WO | claimed |
| WO-2001032101-A1 | BONE HEMOSTASIS METHOD AND MATERIALS | CHILDREN'S HOSPITAL LOS ANGELES (US) | 2001-05-10 | — | — | WO | claimed |