Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379215 | 0.83 | KMT2A (0.38) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL18379081 | 0.79 | PLAU (0.40) | PLAU | |
| SCHEMBL16722630 | 0.77 | PLAU (0.36) | PLAUADH1BADH1CADH1AADH7 | |
| SCHEMBL30461483 | 0.73 | ADH1B (0.32) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL25262321 | 0.73 | ADH1B (0.32) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL30481308 | 0.72 | PLAU (0.43) | PLAU | |
| SCHEMBL25224414 | 0.72 | PLAU (0.43) | PLAU | |
| SCHEMBL20188949 | 0.72 | PLAU (0.43) | PLAU | |
| SCHEMBL23706067 | 0.72 | PLAU (0.43) | PLAU | |
| SCHEMBL31091988 | 0.72 | PLAU (0.43) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017007700-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2017-01-12 | — | — | WO | disclosed |