Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 4/20 | 0.40 |
| ▸ | CLTC | Q00610 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379167 | 0.86 | STAT3 (0.54) | STAT3HIF1ATERTCLTCCA12 | |
| SCHEMBL9986058 | 0.85 | CA12 (0.37) | STAT3HIF1ATERTCA12CA1 | |
| SCHEMBL19237463 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL22015900 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL7487209 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL15764531 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL12869474 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL15810567 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL7485582 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT | |
| SCHEMBL17190576 | 0.83 | HIF1A (0.42) | STAT3HIF1ATERTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354356-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2020-11-12 | — | — | US | disclosed |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2018-07-19 | — | — | US | disclosed |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2018-07-19 | — | — | US | disclosed |
| WO-2017008074-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354356-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | NCS1, DAXX, CNDP2 | STAT3 4101/4885HIF1A 3544/4885TERT 3724/4885 |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | NCS1, DAXX, CNDP2 | STAT3 4101/4885HIF1A 3544/4885TERT 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.