Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168906 | 0.99 | CYP19A1 (0.51) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL22037596 | 0.81 | PDK2 (0.48) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL19039924 | 0.80 | CYP11B2 (0.69) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL15423221 | 0.80 | MEN1 (0.40) | CYP19A1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL22038957 | 0.80 | CYP19A1 (0.47) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL22227771 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL22372453 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL31355554 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL31355556 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH | |
| SCHEMBL31355558 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP11B2CYP11B1CYP17A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9548456-B2 | Organic compound and organic light emitting diode device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-01-17 | — | — | US | disclosed |