Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773429 | 0.88 | POLB (0.33) | SRD5A1POLBALDH1A1KDM4EGAA | |
| SCHEMBL11809602 | 0.86 | SRD5A1 (0.45) | SRD5A1POLBXDHGABRA1GABRB2 | |
| SCHEMBL1083364 | 0.83 | HPGD (0.35) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4208635 | 0.80 | ESR1 (0.39) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30114992 | 0.77 | SRD5A1 (0.45) | SRD5A1POLBXDHGABRA1GABRB2 | |
| SCHEMBL5849188 | 0.77 | SRD5A1 (0.45) | SRD5A1POLBXDHGABRA1GABRB2 | |
| SCHEMBL6591933 | 0.75 | SRD5A1 (0.47) | SRD5A1POLBXDHGABRA1GABRB2 | |
| SCHEMBL7604874 | 0.75 | IGF1R (0.36) | POLBALDH1A1GAAHPGDCYP3A4 | |
| SCHEMBL8443514 | 0.75 | HPGD (0.41) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL9706720 | 0.74 | POLB (0.36) | SRD5A1POLBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601195-B1 | TANDEM PROCESS FOR PREPARING N-ALKYL MORPHINANS | MALLINCKRODT LLC (US) | 2014-04-23 | — | — | EP | claimed |
| EP-1820790-B1 | 3-alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | INVISTA TECH SARL (CH) | 2011-05-11 | — | — | EP | claimed |
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | claimed |
| EP-0574957-B1 | Acrylonitrile- and polyvinylidene fluoride-derived membranes | WEIZMANN KIRYAT MEMBRANE PROD (IL) | 2002-01-02 | — | — | EP | claimed |
| EP-2262822-B1 | ALKYL AND/OR ALKENYL ETHER OF AKLYL AND/OR ALKENYL(POLY)GLYCOSIDES AND USE THEREOF | COGNIS IP MAN GMBH (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-2262822-A1 | ALKYL AND/OR ALKENYL ETHER OF AKLYL AND/OR ALKENYL(POLY)GLYCOSIDES AND USE THEREOF | Cognis IP Management GmbH (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009127339-A1 | ALKYL AND/OR ALKENYL ETHER OF AKLYL AND/OR ALKENYL(POLY)GLYCOSIDES AND USE THEREOF | COGNIS IP MANAGEMENT GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |
| EP-2110378-A1 | New solubilisers and their use | Cognis IP Management GmbH (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-1512690-B1 | Process for the preparation of 9,10-dihydro-9-oxa-10-organyl-phosphaphenanthren-10-oxide and derivatives thereof | SCHILL & SEILACHER STRUKTOL AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1512690-A1 | Process for the preparation of 9,10-dihydro-9-oxa-10-organyl-phosphaphenanthren-10-oxide and derivatives thereof | Schill + Seilacher "Struktol" Aktiengesellschaft (DE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1062208-A1 | HETARYL-SUBSTITUTED BENZYL PHENYL ETHERS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE FOR COMBATING HARMFUL FUNGI AND ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-27 | — | — | EP | disclosed |
| EP-1000058-A1 | 2- PYRAZOLYL AND TRIAZOLYL-3'-OXYMETHYLENE]-PHENYL-ISOXAZOLONES, TRIAZOLONES AND TETRAZOLONES AS PESTICIDES AND FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005139-A1 | 2-[PYRAZOLYL AND TRIAZOLYL-3'-OXYMETHYLENE]-PHENYL-ISOXAZOLONES, TRIAZOLONES AND TETRAZOLONES AS PESTICIDES AND FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
| EP-0111714-B1 | DYNAMIC MEMBRANES FOR REVERSE OSMOSIS AND ULTRAFILTRATION WITH GOOD FLOW QUALITIES | ALIGENA AG (CH) | 1989-03-01 | — | — | EP | disclosed |
| EP-0061610-B1 | SEMIPERMEABLE MEMBRANES FROM ACRYLONITRILE-BASED POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | ALIGENA AG (CH) | 1986-11-26 | — | — | EP | disclosed |
| EP-0025973-B1 | POROUS SEMIPERMEABLE MEMBRANE BASED ON POLYACRYLONITRILE MODIFIED BY AMIDOXIME GROUPS, PROCESS FOR ITS PREPARATION AND THEIR USE | ALIGENA AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0045837-B1 | REACTIVE DERIVATIVES OF 3-OXA-BICYCLO(4.3.0)-NON-1-ENE-9-ONE, PROCESS FOR THEIR PREPARATION AND THEIR USE | Dr. Willmar Schwabe GmbH & Co. (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0111714-A2 | Dynamic membranes for reverse osmosis and ultrafiltration with good flow qualities | ALIGENA AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0061610-A1 | Semipermeable membranes from acrylonitrile-based polymers, process for their preparation and their use | ALIGENA AG (CH) | 1982-10-06 | — | — | EP | disclosed |
| EP-0025973-A2 | Porous semipermeable membrane based on polyacrylonitrile modified by amidoxime groups, process for its preparation and their use | ALIGENA AG (CH) | 1981-04-01 | — | — | EP | disclosed |