Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838149 | 0.88 | SRD5A1 (0.41) | POLBFFAR4GAAGLAHSD17B10 | |
| SCHEMBL1083364 | 0.87 | HPGD (0.35) | POLBFFAR4TDP1GAASMN1; SMN2 | |
| SCHEMBL9706720 | 0.78 | POLB (0.36) | POLBTDP1SRD5A1 | |
| SCHEMBL1083369 | 0.77 | POLB (0.36) | POLBFFAR4GAAHPGD | |
| SCHEMBL2059594 | 0.77 | POLB (0.33) | POLBFFAR4RECQL | |
| SCHEMBL1734598 | 0.76 | MEN1 (0.35) | POLBFFAR4TDP1GAAGLA | |
| SCHEMBL1734600 | 0.76 | POLB (0.38) | POLBFFAR4TDP1GAA | |
| SCHEMBL729518 | 0.76 | GABRA1 (0.43) | POLBGAAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL28557476 | 0.76 | MYC (0.37) | POLBFFAR4TDP1GAAKDM4E | |
| SCHEMBL18074247 | 0.75 | POLB (0.41) | POLBFFAR4GAAGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489472-B1 | Carbonylation process and catalyst composition | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | EP | claimed |
| EP-0489472-A2 | Carbonylation process and catalyst composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-10 | — | — | EP | claimed |