SCHEMBL183840

SCHEMBL183840

C=Cc1ccccc1C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ESR2 Q92731 1/20 0.36
IMPDH2 P12268 2/20 0.35
IMPDH1 P20839 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MCL1 Q07820 1/20 0.34
HTT P42858 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30536365 1.00 TSHR (0.44) TSHRALDH1A1SMN1; SMN2CA1CA2
Benzene SCHEMBL28861778 0.98 TSHR (0.43) TSHRALDH1A1SMN1; SMN2CA1CA2
Butadiene SCHEMBL6839102 0.96 ALDH1A1 (0.41) TSHRALDH1A1SMN1; SMN2CA1CA2
Acrylonitrile SCHEMBL28064833 0.94 ALDH1A1 (0.40) TSHRALDH1A1SMN1; SMN2CA1CA2
Styrene SCHEMBL10457520 0.90 ALDH1A1 (0.54) TSHRALDH1A1SMN1; SMN2CA1CA2
Isopropyl Alcohol SCHEMBL11293168 0.90 TSHR (0.42) TSHRALDH1A1SMN1; SMN2CA1CA2
SCHEMBL28191077 0.87 TSHR (0.35) TSHRALDH1A1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL28093719 0.85 CA1 (0.51) ALDH1A1CA1CA2IMPDH2IMPDH1
SCHEMBL11216851 0.82 TSHR (0.41) TSHRALDH1A1SMN1; SMN2CA1CA2
SCHEMBL60842 0.80 SMN1; SMN2 (0.37) TSHRALDH1A1SMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3246 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058732-A Alpha-cyano styrene optical switch molecule based on visible light regulation and control as well as preparation and application thereof 东南大学 2025-05-30 CN claimed
CN-118834636-B Negative electrode binder, negative electrode coating composition, negative electrode plate and secondary battery 深圳好电科技有限公司 2025-02-18 CN claimed
CN-119286538-A Thermochromic and fluorescent dual-response porous liquid crystal material and preparation method and application thereof 苏州玉晶策新材料科技有限公司 2025-01-10 CN claimed
WO-2024258457-A1 ISOCYANATE-REACTIVE COMPOSITIONS, RIGID POLYURETHANE FOAMS AND METHODS FOR THEIR PRODUCTION COVESTRO LLC (US) 2024-12-19 WO claimed
CN-118834636-A Negative electrode binder, negative electrode coating composition, negative electrode plate and secondary battery 深圳好电科技有限公司 2024-10-25 CN claimed
CN-118813182-A Negative electrode binder, negative electrode coating composition, negative electrode plate and lithium ion battery 深圳好电科技有限公司 2024-10-22 CN claimed
CN-118496435-B Functional polymer, preparation method and application thereof, tin powder modification method and tin paste 化学与精细化工广东省实验室 2024-10-01 CN claimed
CN-118652679-A Light capturing system based on column arene and cyanostyrene derivative, and preparation method and application thereof 常州大学 2024-09-17 CN claimed
CN-118496435-A Functional polymer, preparation method and application thereof, tin powder modification method and tin paste 化学与精细化工广东省实验室 2024-08-16 CN claimed
CN-115232256-B Preparation method of high-resilience polymer polyol, polymer polyol obtained by preparation method and application 中国石油化工股份有限公司 2024-07-23 CN claimed
EP-0159398-B1 DEEP-DRAWABLE FILMS AND SHAPED BODIES FOR VEHICLE INTERIORS MADE FROM THESE FILMS ALKOR GMBH KUNSTSTOFFE (DE) 1989-07-19 EP claimed
EP-0171655-B1 LAMINATED FOAM FILM OR WEB ALKOR GMBH KUNSTSTOFFE (DE) 1988-06-01 EP claimed
EP-0245021-A2 Curable latex composition, films and foams formed therefrom and method for curing the composition THE DOW CHEMICAL COMPANY (US) 1987-11-11 EP claimed
EP-0107090-B1 BIREFRINGENCE COMPENSATING ARRANGEMENT OF PLASTIC SHEETS BAYER AG (DE) 1987-07-22 EP claimed
US-4639473-A BLEND HAVING HIGH IMPACT STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 1987-01-27 US claimed
US-4636546-A LATEX, POLYURETHANE, POLYISOCYANATE ROHM AND HAAS COMPANY (US) 1987-01-13 US claimed
EP-0099455-B1 COMPOSITE SHEET ALKOR GMBH KUNSTSTOFFE (DE) 1986-10-29 EP claimed
US-4617254-A Process for forming detailed images CHISSO CORPORATION (JP) 1986-10-14 US claimed
US-4568722-A Polymer compositions containing styrene/cyanostyrene copolymers ATLANTIC RICHFIELD COMPANY (US) 1986-02-04 US claimed
US-3969433-A ADDITION POLYMER KOSE AKIRA 1976-07-13 US claimed