Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | COMT | P21964 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30627023 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2COMTALDH1A1PKMTSHR | |
| SCHEMBL18384524 | 0.80 | MAPT (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL18384499 | 0.80 | KDM4E (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL18384698 | 0.77 | KDM4E (0.43) | SMN1; SMN2ALDH1A1PKMTDP1CSNK2A2 | |
| SCHEMBL30626980 | 0.77 | KDM4E (0.43) | SMN1; SMN2ALDH1A1PKMTDP1CSNK2A2 | |
| SCHEMBL18384536 | 0.74 | KDM4E (0.48) | SMN1; SMN2ALDH1A1PKMCSNK2A2KDR | |
| SCHEMBL18384704 | 0.73 | KDR (0.43) | SMN1; SMN2ALDH1A1PKMTDP1CSNK2A2 | |
| SCHEMBL30626981 | 0.73 | KDR (0.43) | SMN1; SMN2ALDH1A1PKMTDP1CSNK2A2 | |
| SCHEMBL30626987 | 0.73 | CSNK2A2 (0.43) | SMN1; SMN2ALDH1A1PKMTSHRTDP1 | |
| SCHEMBL9432296 | 0.72 | CSNK2A2 (0.41) | SMN1; SMN2ALDH1A1PKMTSHRCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947879-A | BBI608 derivative, preparation method thereof and application thereof in preparing medicines for treating STAT3 mediated diseases | 沈阳药科大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-3127907-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | Boston Biomedical, Inc. (US) | 2017-02-08 | — | — | EP | disclosed |
| EP-3127907-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | Boston Biomedical, Inc. (US) | 2017-02-08 | — | — | EP | disclosed |
| US-20170015677-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | BOSTON BIOMEDICAL, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-20170015677-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | BOSTON BIOMEDICAL, INC. (US) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015677-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | NQO1, SQOR, SULT1E1 | SMN1; SMN2 3746/4885COMT 534/4885ALDH1A1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.