SCHEMBL183853

SCHEMBL183853

N=C(N)c1ccccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
F2 P00734 3/20 0.46
F10 P00742 2/20 0.46
F12 P00748 1/20 0.46
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
PKM P14618 1/20 0.46
ALOX15 P16050 3/20 0.45
CYP3A4 P08684 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 5/20 0.45
HSD17B10 Q99714 5/20 0.45
CFTR P13569 1/20 0.45
BLM P54132 1/20 0.44
PRSS1 P07477 3/20 0.42
PRSS3 P35030 2/20 0.42
PRSS2 P07478 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1313681 0.97 BLM (0.48) MAPTGAAF2F10F12
Hydrochloric Acid SCHEMBL640309 0.97 BLM (0.48) MAPTGAAF2F10F12
SCHEMBL10495281 0.83 F2 (0.55) MAPTF2F10F12F7
SCHEMBL28979743 0.83 MAPT (0.57) MAPTGAAALOX15CYP3A4SMN1; SMN2
Hydrochloric Acid SCHEMBL28555632 0.80 BLM (0.57) MAPTF2F10F12F7
Hydrochloric Acid SCHEMBL29008442 0.80 BLM (0.57) MAPTF2F10F12F7
SCHEMBL1302674 0.80 F2 (0.42) F2F10F12F7F3
Hydrochloric Acid SCHEMBL7512055 0.78 PRSS1 (0.42) F2F10F12F7F3
Hydrochloric Acid SCHEMBL1304204 0.78 PRSS1 (0.42) F2F10F12F7F3
SCHEMBL458997 0.78 F2 (0.41) MAPTGAAF2F10F12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059837-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL IN THE BOWL ANIMAL HEALTH, INC. (US) 2024-03-21 WO claimed
CN-114845471-B Oil removing and hole finishing method for PTH (plated through hole) process of printed circuit board, alkaline oil removing and hole finishing agent and preparation method thereof 深圳市板明科技股份有限公司 2022-09-27 CN claimed
CN-114845471-A Oil removing and hole finishing method for PTH (plated through hole) process of printed circuit board, alkaline oil removing and hole finishing agent and preparation method thereof 深圳市板明科技股份有限公司 2022-08-02 CN claimed
CN-106544339-B It is a kind of for extracting the kit of animal tissue DNA 郑州中道生物技术有限公司 2019-05-31 CN claimed
CN-105087552-B A method of extraction animal tissue nucleic acid 河南中标检测服务有限公司 2018-08-17 CN claimed
EP-3325618-A1 NOVEL TRYPSIN ISOFORMS AND THEIR USE Enzymatica AB (SE) 2018-05-30 EP claimed
CN-105112404-B A kind of preparation method of animal tissue's nucleic acid extraction liquid 河南中标检测服务有限公司 2018-02-27 CN claimed
CN-106544339-A A kind of test kit for extracting animal tissue DNA 郑州中道生物技术有限公司 2017-03-29 CN claimed
WO-2017017012-A1 NOVEL TRYPSIN ISOFORMS AND THEIR USE Zymetech ehf. (IS) 2017-02-02 WO claimed
CN-105112404-A Preparation method of nucleic acid extracting solution for animal tissues ZHONGBIAO TESTING HENAN SERVICE LTD 2015-12-02 CN claimed
US-4661224-A AFFINITY CHROMATOGRAPHY IONICS, INCORPORATED (US) 1987-04-28 US claimed
US-4643814-A AFFINITY CHROMATOGRAPHY IONICS, INCORPORATED (US) 1987-02-17 US claimed
US-4594135-A Ion permeable barrier IONICS INCORPORATED (US) 1986-06-10 US claimed
US-4584075-A Process and apparatus for electrically desorbing components selectively sorbed on an electrolytically conducting barrier IONICS INCORPORATED (US) 1986-04-22 US claimed
EP-0056210-B1 METHOD FOR THE FLUORIMETRIC DETERMINATION OF ENDOTOXINS, PEPTIDES CONTAINING A FLUOROPHORE USED IN THE SAID METHOD AND THEIR METHOD OF PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-03-12 EP claimed
EP-0002723-B1 PHOSPHONYL-UREIDO-BENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION IN DRUGS BAYER AG (DE) 1981-01-21 EP claimed
EP-0002723-A1 Phosphonyl-ureido-benzene derivatives, process for their preparation and their application in drugs BAYER AG (DE) 1979-07-11 EP claimed
US-4018814-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-19 US claimed
US-4013676-A NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed
US-3996247-A ANTHELMINTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed