Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979741 | 0.79 | MAPT (0.59) | F2PRSS1PRSS3PRSS2MMP2 | |
| SCHEMBL1302674 | 0.79 | F2 (0.42) | F2PRSS1PLGPLAUPLAT | |
| SCHEMBL183853 | 0.78 | MAPT (0.46) | F2PRSS1PLGPLAUPLAT | |
| SCHEMBL10495291 | 0.77 | ALDH1A1 (0.41) | F2PLGPLAUPLATKLK1 | |
| Hydrochloric Acid SCHEMBL7512055 | 0.77 | PRSS1 (0.42) | F2PRSS1PLGPLAUPLAT | |
| Hydrochloric Acid SCHEMBL1304204 | 0.77 | PRSS1 (0.42) | F2PRSS1PLGPLAUPLAT | |
| Hydrochloric Acid SCHEMBL1313681 | 0.76 | BLM (0.48) | F2PRSS1PLGPLAUPLAT | |
| Hydrochloric Acid SCHEMBL640309 | 0.76 | BLM (0.48) | F2PRSS1PLGPLAUPLAT | |
| Hydrochloric Acid SCHEMBL8378249 | 0.76 | ALOX15 (0.46) | F2PRSS1PLGPLAUPLAT | |
| Hydrochloric Acid SCHEMBL7799648 | 0.76 | PRSS1 (0.41) | F2PRSS1PLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011118818-A8 | AMIDINOANILINE DERIVATIVE | 味の素株式会社 (JP) | 2012-01-26 | — | — | WO | disclosed |