SCHEMBL183897

SCHEMBL183897

COc1cccc(-c2ccccn2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.66
CLK4 Q9HAZ1 1/20 0.66
RAB9A P51151 4/20 0.65
NPC1 O15118 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
PKM P14618 1/20 0.65
GRM5 P41594 1/20 0.65
TGFBR1 P36897 1/20 0.60
TOP1 P11387 1/20 0.57
CYP19A1 P11511 1/20 0.56
LMNA P02545 2/20 0.55
HPGD P15428 2/20 0.55
MAPT P10636 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
MEN1 O00255 1/20 0.55
GAA P10253 1/20 0.55
KMT2A Q03164 1/20 0.55
DCTPP1 Q9H773 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ABL1 P00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496945 1.00 DYRK1A (0.66) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL6831093 0.98 DYRK1A (0.64) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL2485408 0.98 DYRK1A (0.64) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
Phenol SCHEMBL28131268 0.91 NPC1 (0.56) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL17779985 0.86 ABCB1 (0.55) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL16109068 0.86 CES2 (0.66) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL31187765 0.85 GRM5 (0.49) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL8248415 0.85 NPC1 (0.52) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL28208710 0.85 CYP1A2 (0.56) DYRK1ACLK4RAB9ANPC1SMN1; SMN2
SCHEMBL17500184 0.85 GRM5 (0.49) DYRK1ACLK4RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
CN-117924157-A Compound, preparation method thereof and application thereof in tetravalent plutonium separation 中国原子能科学研究院 2024-04-26 CN claimed
CN-104356053-A Preparation method of 2-(3-halogen phenyl) pyridine derivative UNIV TIANJIN 2015-02-18 CN claimed
EP-4540258-B1 RUTHENIUM COMPLEXES AND THEIR USES IN CHEMICAL REACTIONS UNIV MANCHESTER (GB) 2026-04-15 EP disclosed
US-20250242335-A1 CATALYST UNIV MANCHESTER (GB) 2025-07-31 US disclosed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO disclosed
US-12157748-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-12-03 US disclosed
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-10-31 US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 US disclosed
US-20040247934-A1 Light emitting material and organic light-emitting device SAMSUNG ELECTRONICS CO., LTD (KR) 2004-12-09 US disclosed
CN-1554128-A Light emitting material and organic light-emitting device �Ѻ͵繤��ʽ���� 2004-12-08 CN disclosed
EP-1424350-A1 PHOSPHOR LIGHT−EMITTING COMPOUND, PHOSPHOR LIGHT−EMITTING COMPOSITION, AND ORGANIC LIGHT EMITTING ELEMENT NIPPON HOSO KYOKAI (JP) 2004-06-02 EP disclosed
EP-1407501-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE Showa Denko K.K. (JP) 2004-04-14 EP disclosed
WO-2003092334-A1 PHOSPHORESCENT POLYMER COMPOUND, LIGHT EMITTING MATERIAL AND ORGANIC ELECTROLUMINESCENT (EL) DEVICE USING THE COMPOUND NIPPON HOSO KYOKAI (JP) 2003-11-06 WO disclosed
US-20030091862-A1 Phosphorescent compound, a phosphorescent composition and an organic light-emitting device NIPPON HOSO KYOKAI 2003-05-15 US disclosed
WO-2003001616-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2003-01-03 WO disclosed
CN-1046218-C Process for the carbonylation of acetylenically unsaturated compounds SHELL INT RESEARCH (NL) 1999-11-10 CN disclosed
CN-1088851-A The catalyst system that the carbonylation of acetylenically unsaturated compound is used SHELL INT RESEARCH (NL) 1994-07-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12157748-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC DYRK1A 4512/4885CLK4 3091/4885RAB9A 2247/4885
US-12037348-B2 Blue and narrow band green and red emitting metal complexes OCIAD2, OCIAD1, ORC3 DYRK1A 3604/4885CLK4 2002/4885RAB9A 2201/4885
US-20250242335-A1 CATALYST CYP1A1, CYP1A2, CYP2B6 DYRK1A 4133/4885CLK4 3252/4885RAB9A 1852/4885
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES OCIAD2, OCIAD1, ORC3 DYRK1A 3604/4885CLK4 2002/4885RAB9A 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.