Glycolic Acid

Glycolic Acid

SCHEMBL1839458

COC(C)NC(C)OC.O=C(O)CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TGFBR1 P36897 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
PTGS2 P35354 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL1832890 0.86 FFAR3 (0.48) TSHREGLN1ALDH1A1LMNAMAPT
Succinic Acid SCHEMBL1833033 0.86 EGLN1 (0.43) TSHREGLN1ALDH1A1LMNAGABRP
Succinic Acid SCHEMBL1833026 0.86 EGLN1 (0.43) TSHREGLN1ALDH1A1LMNAGABRP
Bicarbonate SCHEMBL1834590 0.85 ALDH1A1 (0.35) TSHRALDH1A1CYP2D6CYP2C19SMN1; SMN2
Bicarbonate SCHEMBL1831708 0.85 ALDH1A1 (0.35) TSHRALDH1A1CYP2D6CYP2C19SMN1; SMN2
Acetic Acid SCHEMBL1838385 0.82 ALDH1A1 (0.40) TSHRALDH1A1SMN1; SMN2
Oxalic Acid SCHEMBL1835274 0.82 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2CYP1A2
Oxalic Acid SCHEMBL1835265 0.82 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2CYP1A2
Butyric Acid SCHEMBL1834161 0.80 FFAR3 (0.54) TSHRALDH1A1TDP1GABRPGABRD
Citric Acid SCHEMBL1833603 0.80 ALDH1A1 (0.56) TSHRALDH1A1LMNAMAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
EP-1948589-A1 IONIC LIQUIDS Bioniqs Limited (GB) 2008-07-30 EP disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed
WO-2007036712-A1 IONIC LIQUIDS BIONIQS LIMITED (GB) 2007-04-05 WO disclosed