Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396103 | 1.00 | MEN1 (0.32) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18395910 | 0.96 | MEN1 (0.32) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18395912 | 0.96 | MEN1 (0.32) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18396185 | 0.91 | LMNA (0.33) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18396187 | 0.91 | LMNA (0.33) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18394499 | 0.82 | — | — | |
| SCHEMBL18394500 | 0.82 | — | — | |
| SCHEMBL18396152 | 0.82 | LMNA (0.35) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL18394649 | 0.78 | — | — | |
| SCHEMBL18395240 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10077323-B2 | Polymers functionalized with imine compounds containing a protected thiol group | BRIDGESTONE CORPORATION (JP) | 2018-09-18 | — | — | US | disclosed |
| US-20170022301-A1 | POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A PROTECTED THIOL GROUP | BRIDGESTONE CORPORATION (JP) | 2017-01-26 | — | — | US | disclosed |