Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31231118 | 0.86 | GAA (0.56) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL6949718 | 0.86 | GAA (0.56) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL30686655 | 0.86 | GAA (0.56) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL10747419 | 0.83 | GAA (0.44) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL28402121 | 0.83 | LMNA (0.51) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL13444005 | 0.82 | GAA (0.42) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL30587182 | 0.79 | SMN1; SMN2 (0.49) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL6951228 | 0.79 | SMN1; SMN2 (0.49) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL28402122 | 0.79 | LMNA (0.50) | GAAPOLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL13410042 | 0.78 | GAA (0.47) | GAAPOLBSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302002-A1 | Pharmaceutical Compositions and Methods for Stabilizing the Same | Chisei Farmaceutici S.p.A. (IT) | 2023-09-28 | — | — | US | disclosed |
| US-20190117660-A1 | Pharmaceutical Compositions and Methods for Stabilizing the Same | CHIESI FARMACEUTICI S.P.A. (IT) | 2019-04-25 | — | — | US | disclosed |
| US-20120322836-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR STABILIZING THE SAME | THE MEDICINES COMPANY | 2012-12-20 | — | — | US | disclosed |
| EP-2320739-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR STABILIZING THE SAME | The Medicines Company (US) | 2011-05-18 | — | — | EP | disclosed |
| US-20100105743-A1 | Pharmaceutical compositions and methods for stabilizing the same | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-04-29 | — | — | US | disclosed |
| WO-2010014234-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR STABILIZING THE SAME | THE MEDICINES COMPANY (US) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105743-A1 | Pharmaceutical compositions and methods for stabilizing the same | RPS24, DHCR24, RPL24 | GAA 342/4885POLB 939/4885SMN1; SMN2 2557/4885 |
| US-20190117660-A1 | Pharmaceutical Compositions and Methods for Stabilizing the Same | RPS24, DHCR24, RPL24 | GAA 342/4885POLB 939/4885SMN1; SMN2 2557/4885 |
| US-20120322836-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR STABILIZING THE SAME | RPS24, DHCR24, RPL24 | GAA 342/4885POLB 939/4885SMN1; SMN2 2557/4885 |
| US-20230302002-A1 | Pharmaceutical Compositions and Methods for Stabilizing the Same | RPS24, DHCR24, RPL24 | GAA 342/4885POLB 939/4885SMN1; SMN2 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.