Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22608972 | 0.75 | KDM4E (0.47) | — | |
| SCHEMBL27403589 | 0.75 | CYP2D6 (0.65) | DRD2DRD3HTR1A | |
| SCHEMBL2599485 | 0.75 | CYP2D6 (0.65) | DRD2DRD3HTR1A | |
| SCHEMBL18399110 | 0.75 | SLC6A2 (0.50) | DRD3 | |
| Hydrochloric Acid SCHEMBL2599502 | 0.74 | CYP2D6 (0.63) | DRD2DRD3HTR1A | |
| SCHEMBL28852285 | 0.72 | — | — | |
| SCHEMBL27471534 | 0.71 | TAAR1 (0.50) | DRD2DRD3 | |
| SCHEMBL22873482 | 0.71 | KDM1A (0.41) | — | |
| SCHEMBL14737700 | 0.71 | NOS1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL21796719 | 0.70 | KDM1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325449-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012576-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-01-26 | — | — | WO | disclosed |