Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399460 | 0.83 | ALDH1A1 (0.44) | NR1H2LMNAALDH1A1TYRHSD17B10 | |
| SCHEMBL18399484 | 0.81 | HSP90AA1 (0.42) | LMNAALDH1A1TYRHSD17B10ALOX15 | |
| SCHEMBL18400633 | 0.79 | NR1H2 (0.47) | NR1H2LMNAALDH1A1TYRHSD17B10 | |
| SCHEMBL316680 | 0.79 | ALDH1A1 (0.59) | LMNAALDH1A1TYRHSD17B10ALOX15 | |
| SCHEMBL14283783 | 0.78 | ALDH1A1 (0.71) | LMNAALDH1A1TYRHSD17B10ALOX15 | |
| SCHEMBL12733343 | 0.76 | NR1H2 (0.52) | NR1H2LMNAALDH1A1TYRHSD17B10 | |
| SCHEMBL7160236 | 0.75 | ALDH1A1 (0.50) | LMNAALDH1A1TYRHSD17B10ALOX15 | |
| SCHEMBL18399463 | 0.75 | HSP90AA1 (0.45) | NR1H2LMNAALDH1A1TYRHSD17B10 | |
| SCHEMBL7200768 | 0.74 | NR1H2 (0.67) | NR1H2LMNAALDH1A1TYRHSD17B10 | |
| SCHEMBL11588522 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1TYRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550711-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-01-24 | — | — | US | disclosed |