Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021910 | 0.88 | HTR2A (0.65) | GPR84SLC6A4HTR2ATRPM8TP53 | |
| SCHEMBL3182374 | 0.84 | GPR84 (0.67) | GPR84SLC6A4HTR2AADRB3HTR2C | |
| SCHEMBL27480459 | 0.83 | HTR2A (0.67) | SLC6A4HTR2AADRB3MTNR1AMTNR1B | |
| SCHEMBL3181757 | 0.82 | GPR84 (0.69) | GPR84SLC6A4HTR2ATRPM8ADRB3 | |
| SCHEMBL25139565 | 0.80 | GPR84 (0.56) | GPR84SLC6A4HTR2ATRPM8ADRB3 | |
| SCHEMBL23029721 | 0.79 | HTR2A (0.69) | GPR84SLC6A4HTR2ATRPM8MTNR1A | |
| SCHEMBL23649381 | 0.79 | HTR2A (0.74) | GPR84SLC6A4HTR2ATRPM8MTNR1A | |
| SCHEMBL24452687 | 0.79 | GPR84 (0.69) | GPR84SLC6A4HTR2ATRPM8ADRB3 | |
| SCHEMBL7716375 | 0.79 | GPR84 (0.69) | GPR84SLC6A4HTR2ATRPM8MTNR1A | |
| SCHEMBL1971111 | 0.79 | HTR2A (0.76) | GPR84SLC6A4HTR2ATRPM8HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551721-B2 | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-01-24 | — | — | US | disclosed |
| US-9551721-B2 | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-01-24 | — | — | US | disclosed |