SCHEMBL18399600

SCHEMBL18399600

CC/C(=C(\CC)C(C)(C)C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053081 1.00 TSHR (0.33) TSHRTDP1
SCHEMBL18766590 0.79 ALDH1A1 (0.30) TDP1
SCHEMBL19199589 0.79 ALDH1A1 (0.30) TDP1
SCHEMBL19349775 0.79
SCHEMBL27672830 0.76
SCHEMBL19059707 0.74 ALDH1A1 (0.34) TSHR
SCHEMBL23111415 0.67 TSHR (0.33) TSHRTDP1
SCHEMBL396944 0.67
SCHEMBL163361 0.64
SCHEMBL4655335 0.62 TSHR (0.38) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024023276-A1 ROCK2 INHIBITORS FOR THE TREATMENT OF VIRAL INFECTIONS GRAVITON BIOSCIENCE BV (NL) 2024-02-01 WO disclosed
US-9550765-B2 Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors INCYTE HOLDINGS CORPORATION (US) 2017-01-24 US disclosed