SCHEMBL184

SCHEMBL184

On1nnc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 1.00
MAPK1 P28482 1/20 1.00
ATM Q13315 1/20 1.00
DGAT1 O75907 1/20 0.61
SLC9A1 P19634 7/20 0.56
KEAP1 Q14145 1/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
MAPT P10636 1/20 0.56
CYP2C9 P11712 1/20 0.56
THPO P40225 1/20 0.56
CYP4Z1 Q86W10 1/20 0.56
KCNMA1 Q12791 3/20 0.50
MGAM O43451 2/20 0.48
AMY1A P0DUB6 2/20 0.48
GAA P10253 2/20 0.48
SI P14410 2/20 0.48
MGAM2 Q2M2H8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012471 1.00 POLB (1.00) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL3672275 1.00 POLB (1.00) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL7424280 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
Water SCHEMBL12099335 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
Ammonia Solution, Strong SCHEMBL563462 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
Phosphine SCHEMBL23702726 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL3367761 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL6827564 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL875075 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1
SCHEMBL875034 0.98 POLB (0.95) POLBMAPK1ATMDGAT1SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 182074 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122082136-A Method for preparing high-purity regenerated cellulose fibers by using waste cotton textiles 2026-05-26 CN claimed
CN-120617300-B Application of BSP-MA/HA-NB hydrogel in preparation of medicines for treating bone defect, cartilage injury or articular cartilage degenerative diseases Sichuan Orthopaedic Hospital (Chengdu Sports Hospital, Chengdu Sports Trauma Research Institute) (CN) 2026-05-26 CN claimed
CN-122080119-A Synthesis method of MC-Gly-Gly-Phe-Gly tetrapeptide linker 2026-05-26 CN claimed
CN-122080527-A Wear-resisting high-voltage composite silica gel insulating sleeve 2026-05-26 CN claimed
CN-122079965-A Mitochondria-targeted paclitaxel derivative and preparation method and application thereof 2026-05-26 CN claimed
CN-122079809-A Synthesis method of dipeptide linker of antibody coupling degradation agent 2026-05-26 CN claimed
CN-118001240-B Podophyllotoxin-9-fluorenylmethanol small molecule prodrug nanoparticle and preparation method and application thereof SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-120511435-B Lithium ion battery diaphragm based on composite coating and preparation method and application thereof Shanxi Housheng New Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080614-A PEG/PEI nanocomposite based on carboxymethyl cellulose and preparation method and application thereof 2026-05-26 CN claimed
CN-117462678-B Pt (platinum)2+Carbon dot @ protoporphyrin acoustic power drug-carrying system and preparation method and application thereof Shanxi Liuwei artificial intelligence Biomedical Research Institute (CN) 2026-05-26 CN claimed
US-4105652-A Synthesis of human β-endorphin HOFFMANN-LA ROCHE INC. (US) 1978-08-08 US claimed
US-4101380-A USING POLYOXYETHYLENE GLYCOL DERIVATIVES AND ACTIBATED CARBOXYLIC ESTERS RESEARCH PRODUCTS REHOVOT LTD. (IL) 1978-07-18 US claimed
US-4098777-A OLIGOPEPTIDES, TREATMENT OF AUTOIMMUNE DISEASES MERCK & CO., INC. (US) 1978-07-04 US claimed
US-4087283-A CARBODIIMIDE AND N-HYDROXY CYCLIC AMINE GAF CORPORATION (US) 1978-05-02 US claimed
US-4060551-A Method of producing pantethine SOGO PHARMACEUTICAL COMPANY LIMITED (JA) 1977-11-29 US claimed
US-4045384-A Method for forming an amide bond between a latex and protein THE DOW CHEMICAL COMPANY (US) 1977-08-30 US claimed
US-4029642-A CONDENSATION OF DES-B OCTAPEPTIDE WITH A PEPTIDE HOECHST AKTIENGESELLSCHAFT (DT) 1977-06-14 US claimed
US-3963691-A POLYPEPTIDES, PEPTIZATION MERCK & CO., INC. (US) 1976-06-15 US claimed
US-3953417-A Synthetically modified trypsin inhibitors and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-27 US claimed
US-3950301-A HYDROXYBENZOTRIAZOLES, FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1976-04-13 US claimed