Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.95 |
| ▸ | ATM | Q13315 | 1/20 | 0.95 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.59 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672275 | 0.98 | POLB (1.00) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL184 | 0.98 | POLB (1.00) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL1012471 | 0.98 | POLB (1.00) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL875075 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL3367761 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| Phosphine SCHEMBL23702726 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| Ammonia Solution, Strong SCHEMBL563462 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| Water SCHEMBL12099335 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL6827564 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL875034 | 0.95 | POLB (0.95) | POLBMAPK1ATMDGAT1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707564-B1 | DIFLUORO STATONE ANALOGS | MERRELL PHARMA INC (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6114380-A | ANTIVIRAL AGENT; ADMINISTERING TO TREAT HIV INFECTION; N-(4-(N-BENZYLOXYCARBONYL-L-VALYL)AMINO-2,2-DIFLUORO-1,3-DIOXO-5-(4-(2-N -MORPHOLYL)ETHYLOXY)PHENYL-PENTYL)-O-((2-PYRIDYL)METHYL)-D-VALINOL, FOR EXAMPLE | MERRELL PHARMACEUTICALS INC. (US) | 2000-09-05 | — | — | US | disclosed |
| US-5717093-A | VIRICIDE | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0707564-A1 | DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001958-A1 | DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-19 | — | — | WO | disclosed |