Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17313590 | 0.89 | ABL1 (0.48) | NFE2L2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL17313591 | 0.89 | ABL1 (0.48) | NFE2L2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL17313637 | 0.84 | NPBWR1 (0.38) | RAB9AMAPTMEN1KMT2ALMNA | |
| SCHEMBL17420242 | 0.79 | ABL1 (0.53) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1773116 | 0.78 | CYP1A2 (0.42) | ALDH1A1GAATDP1 | |
| SCHEMBL18403125 | 0.77 | MEN1 (0.55) | RAB9AMAPTMEN1KMT2ALMNA | |
| SCHEMBL17313624 | 0.74 | ABL1 (0.46) | — | |
| SCHEMBL15859944 | 0.74 | ABL1 (0.46) | — | |
| SCHEMBL17313583 | 0.74 | ABL1 (0.48) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17313582 | 0.74 | ABL1 (0.48) | MAPTLMNAHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550772-B2 | Azaindole derivatives as multi kinase inhibitors | ORIBASE PHARMA (FR) | 2017-01-24 | — | — | US | disclosed |