SCHEMBL18403140

SCHEMBL18403140

CCC(c1cccc(OC)c1)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.50
CASR P41180 4/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
TAAR1 Q96RJ0 2/20 0.46
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18320847 1.00 AOC3 (0.50) AOC3CASRL3MBTL1TAAR1MTNR1A
SCHEMBL11618270 0.91 AOC3 (0.51) AOC3CASRL3MBTL1TAAR1MTNR1A
SCHEMBL16871059 0.88 CASR (0.48) AOC3CASRL3MBTL1TAAR1
SCHEMBL16871396 0.88 CASR (0.48) AOC3CASRL3MBTL1TAAR1
SCHEMBL12463283 0.86 AOC3 (0.48) AOC3CASRL3MBTL1TAAR1MTNR1A
SCHEMBL15121380 0.86 AOC3 (0.53) AOC3CASRL3MBTL1TAAR1MTNR1A
SCHEMBL2322739 0.86 CASR (0.47) AOC3CASRL3MBTL1TAAR1MTNR1A
SCHEMBL7412592 0.84 TAAR1 (0.56) AOC3CASRL3MBTL1TAAR1
SCHEMBL27536288 0.84 AOC3 (0.49) AOC3CASRL3MBTL1TAAR1ACHE
SCHEMBL2177637 0.83 CASR (0.44) AOC3CASRL3MBTL1TAAR1MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519100-B1 INTERMEDIATE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF TAPENTADOL AND RELATED COMPOUNDS MAPI PHARMA LTD (IL) 2017-03-15 EP disclosed
US-9586914-B2 Modulators of C3a receptors THE UNIVERSITY OF QUEENSLAND (AU) 2017-03-07 US disclosed
US-9550742-B2 11-OXO-10,11-dihydrodibenzo[B,F][1,4]thiazepine S-oxide derivatives and their use as dopamine D2 receptor antagonists THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2017-01-24 US disclosed