Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | ACACB | O00763 | 8/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16122883 | 1.00 | GAA (0.53) | GAARAB9APPARGPPARAACACB | |
| SCHEMBL31370316 | 0.88 | LMNA (0.57) | PPARGACACBITGB3ITGA2BCYP2C19 | |
| SCHEMBL16174167 | 0.88 | ACACB (0.53) | GAARAB9AACACBPLK1 | |
| SCHEMBL15336494 | 0.88 | ACACB (0.53) | GAARAB9AACACBPLK1 | |
| SCHEMBL16173536 | 0.86 | GAA (0.62) | GAARAB9AACACBPLK1 | |
| SCHEMBL18647565 | 0.86 | GAA (0.62) | GAARAB9AACACBPLK1 | |
| SCHEMBL31688723 | 0.86 | PPARG (0.52) | PPARGITGB3ITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL20074215 | 0.86 | ACACB (0.51) | GAARAB9AACACBPLK1 | |
| SCHEMBL16116803 | 0.86 | ACACB (0.53) | RAB9AACACBSUCNR1ALDH1A1POLB | |
| SCHEMBL12597805 | 0.86 | PPARG (0.52) | PPARGITGB3ITGA2BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148692-B1 | MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN | IPSEN PHARMA SAS (FR) | 2017-01-25 | — | — | EP | disclosed |