Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677814 | 0.91 | OPRM1 (0.50) | OPRM1HSD11B1OPRK1OPRL1BCHE | |
| SCHEMBL4677810 | 0.91 | OPRM1 (0.50) | OPRM1HSD11B1OPRK1OPRL1BCHE | |
| SCHEMBL1835708 | 0.89 | OPRM1 (0.57) | OPRM1HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL1835710 | 0.88 | OPRM1 (0.58) | OPRM1HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL1840395 | 0.86 | OPRM1 (0.56) | OPRM1HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL1835021 | 0.86 | OPRM1 (0.56) | OPRM1HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL1840394 | 0.86 | OPRM1 (0.55) | OPRM1HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL1841565 | 0.86 | OPRM1 (0.48) | OPRM1HSD11B1OPRK1OPRL1BCHE | |
| SCHEMBL1833753 | 0.84 | OPRM1 (0.43) | OPRM1HSD11B1OPRK1OPRL1BCHE | |
| SCHEMBL4682975 | 0.83 | CHRM1 (0.52) | OPRM1DRD2DRD3OPRK1PLD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |