Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22808116 | 0.86 | TDP1 (0.41) | PARP1SMN1; SMN2TDP1TP53HDAC8 | |
| SCHEMBL14541399 | 0.83 | AKT1 (0.38) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22548658 | 0.79 | PARP1 (0.41) | PARP1SMN1; SMN2TDP1TP53HDAC8 | |
| SCHEMBL16994800 | 0.77 | PARP1 (0.43) | PARP1SMN1; SMN2TDP1TP53HDAC8 | |
| SCHEMBL22294791 | 0.73 | ELANE (0.37) | PARP1SMN1; SMN2TDP1POLBMAPT | |
| SCHEMBL25467855 | 0.70 | DEGS1 (0.39) | SMN1; SMN2TP53MEN1KMT2AHPGD | |
| SCHEMBL17726089 | 0.70 | PARP1 (0.42) | PARP1SMN1; SMN2TDP1TP53HDAC8 | |
| SCHEMBL15471903 | 0.70 | PARP1 (0.46) | PARP1SMN1; SMN2TDP1HDAC8HDAC6 | |
| SCHEMBL16952628 | 0.70 | TDP1 (0.52) | PARP1SMN1; SMN2TDP1TP53HDAC8 | |
| SCHEMBL14851433 | 0.69 | AKT1 (0.35) | PARP1TDP1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439191-B1 | METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER, METHOD FOR PRODUCING ISOCYANATE USING N-SUBSTITUTED CARBAMIC ACID ESTER, AND COMPOSITION FOR TRANSFERRING AND STORING N-SUBSTITUTED CARBAMIC ACID ESTER CONTAINING N-SUBSTITUTED CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND | ASAHI CHEMICAL IND (JP) | 2017-01-25 | — | — | EP | disclosed |