Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011270 | 0.83 | PARP1 (0.40) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL21003993 | 0.81 | CES2 (0.46) | PARP1HDAC6SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27290043 | 0.74 | TDP1 (0.40) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL19273899 | 0.74 | PARP1 (0.45) | PARP1HDAC8HDAC6SMN1; SMN2POLB | |
| SCHEMBL22548658 | 0.71 | PARP1 (0.41) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL20057542 | 0.71 | PARP1 (0.57) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL18404110 | 0.70 | PARP1 (0.40) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL16994800 | 0.70 | PARP1 (0.43) | PARP1TDP1TP53HDAC8HDAC6 | |
| SCHEMBL25784300 | 0.69 | PARP1 (0.46) | PARP1TDP1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL22808116 | 0.69 | TDP1 (0.41) | PARP1TDP1TP53HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016068451-A1 | ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY APPARATUS | 삼성에스디아이 주식회사 | 2016-05-06 | — | — | WO | disclosed |