Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 6/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108209 | 0.82 | RBP4 (0.78) | RBP4LMNATDP1 | |
| SCHEMBL13073779 | 0.81 | RBP4 (0.54) | RBP4MDM2LMNATP53TSHR | |
| SCHEMBL23434873 | 0.77 | IRAK4 (0.45) | RBP4LMNAENPP2ATXN2 | |
| SCHEMBL3100108 | 0.74 | RBP4 (0.78) | RBP4LMNATDP1 | |
| SCHEMBL18404603 | 0.74 | RBP4 (0.74) | RBP4LMNATDP1 | |
| SCHEMBL18528838 | 0.74 | TDP1 (0.64) | TSHRTDP1PTGDRPTGDR2 | |
| SCHEMBL12409205 | 0.73 | CYP4F2 (0.41) | RBP4ENPP2ATXN2TSHRPTGDR | |
| SCHEMBL3116386 | 0.72 | RBP4 (0.76) | RBP4LMNATDP1 | |
| SCHEMBL13073355 | 0.72 | RBP4 (0.52) | RBP4LMNATP53TSHRPTGDR2 | |
| SCHEMBL3111995 | 0.72 | RBP4 (0.68) | RBP4LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-B1 | HETEROCYCLIC COMPOUND AS BLOOD RBP4 LOWERING AGENT | TAKEDA PHARMACEUTICALS CO (JP) | 2017-01-25 | — | — | EP | disclosed |