Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | RBP4 | P02753 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404637 | 0.87 | DPP4 (0.44) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL18404235 | 0.86 | DPP4 (0.48) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL18404334 | 0.83 | DPP4 (0.47) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL18404311 | 0.83 | DPP4 (0.44) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL3098982 | 0.81 | FFAR1 (0.53) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL13034573 | 0.80 | RBP4 (0.53) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL3106079 | 0.80 | RBP4 (0.64) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL3113607 | 0.79 | DPP4 (0.52) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL3114289 | 0.77 | RBP4 (0.54) | DPP4RBP4FFAR1CYP1A2CYP2D6 | |
| SCHEMBL3110995 | 0.77 | RBP4 (0.49) | DPP4RBP4FFAR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-B1 | HETEROCYCLIC COMPOUND AS BLOOD RBP4 LOWERING AGENT | TAKEDA PHARMACEUTICALS CO (JP) | 2017-01-25 | — | — | EP | disclosed |