Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841296 | 0.90 | RAB9A (0.44) | GPR119RAB9AFAAHTHRBATM | |
| SCHEMBL27747836 | 0.86 | RAB9A (0.43) | GPR119RAB9AFAAHTHRBATM | |
| SCHEMBL1162894 | 0.84 | RAB9A (0.47) | GPR119RAB9ATHRBATML3MBTL1 | |
| SCHEMBL1692765 | 0.82 | RAB9A (0.46) | GPR119RAB9AFAAHTHRBATM | |
| SCHEMBL3132481 | 0.81 | RAB9A (0.44) | GPR119RAB9AFAAHTHRBATM | |
| SCHEMBL8554848 | 0.80 | RAB9A (0.45) | RAB9ATHRBATML3MBTL1HRH3 | |
| SCHEMBL1693216 | 0.79 | RAB9A (0.48) | GPR119RAB9ATHRBATML3MBTL1 | |
| SCHEMBL10089204 | 0.79 | RAB9A (0.48) | GPR119RAB9ATHRBATML3MBTL1 | |
| SCHEMBL4977215 | 0.79 | RAB9A (0.48) | GPR119RAB9ATHRBATML3MBTL1 | |
| SCHEMBL3128112 | 0.79 | RAB9A (0.43) | GPR119RAB9AFAAHTHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320905-A1 | NOVEL ADENINE DERIVATIVES | Smithkline Beecham Corporation (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010018134-A1 | NOVEL ADENINE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |