Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.51 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13559890 | 0.94 | PTPN1 (0.53) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL13559882 | 0.92 | PTPN1 (0.52) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL13559896 | 0.91 | PTPN1 (0.48) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL13559873 | 0.90 | PTPN1 (0.52) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL15882996 | 0.90 | PTPN1 (0.47) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL13559879 | 0.89 | PTPN1 (0.47) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL18411854 | 0.89 | PTPN1 (0.49) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL18407010 | 0.88 | PTPN1 (0.58) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL18407013 | 0.88 | PTPN1 (0.53) | PTPN1F3CYP3A4USP2LMNA | |
| SCHEMBL18411860 | 0.87 | PTPN1 (0.45) | PTPN1F3CYP3A4USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022246-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022246-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | VCAM1, EPCAM, ICAM1 | PTPN1 2251/4885F3 683/4885CYP3A4 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.