Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 12/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407934 | 0.88 | GRM4 (0.41) | GRM4SLC10A1ARNPC1RAB9A | |
| SCHEMBL16257442 | 0.86 | SLC10A1 (0.39) | GRM4SLC10A1XDHKDM1A | |
| SCHEMBL29972074 | 0.86 | SLC10A1 (0.39) | GRM4SLC10A1XDHKDM1A | |
| SCHEMBL21727569 | 0.80 | GRM4 (0.40) | GRM4SLC10A1AR | |
| SCHEMBL18408073 | 0.80 | GRM4 (0.40) | GRM4SLC10A1LMNAAR | |
| SCHEMBL18407961 | 0.79 | GRM4 (0.39) | GRM4SLC10A1AR | |
| SCHEMBL18407927 | 0.77 | ENPP2 (0.39) | SLC10A1LMNANPC1RAB9A | |
| SCHEMBL21727650 | 0.77 | GRM4 (0.37) | GRM4SLC10A1AR | |
| SCHEMBL18408034 | 0.76 | HTT (0.44) | SLC10A1LMNANPC1RAB9A | |
| SCHEMBL21727566 | 0.75 | CYP2C19 (0.39) | SLC10A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | Janssen Sciences Ireland UC (IE) | 2017-01-25 | — | — | EP | disclosed |