SCHEMBL18409873

SCHEMBL18409873

BC1CCC(OC(=O)c2cc(N)cc(N)c2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 4/20 0.53
STS P08842 4/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
HTR3E A5X5Y0 2/20 0.40
HTR3B O95264 2/20 0.40
HTR3A P46098 2/20 0.40
HTR3D Q70Z44 2/20 0.40
HTR3C Q8WXA8 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2C19 P33261 1/20 0.40
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
ST14 Q9Y5Y6 1/20 0.40
NR1I2 O75469 1/20 0.40
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17722780 0.95 SERPINE1 (0.49) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL14828376 0.85 SERPINE1 (0.54) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL27794285 0.84 SERPINE1 (0.53) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL16425683 0.83 SERPINE1 (0.53) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL2808284 0.83 SERPINE1 (0.51) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL12172536 0.82 MEN1 (0.55) SERPINE1STSHTR3EHTR3BHTR3A
SCHEMBL12774834 0.81 SERPINE1 (0.50) SERPINE1STSMEN1KMT2AF2
SCHEMBL11996902 0.81 SERPINE1 (0.50) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL105316 0.80 SERPINE1 (0.49) SERPINE1STSCYP1A2CYP2D6HTR3E
SCHEMBL17720302 0.80 SERPINE1 (0.49) SERPINE1STSCYP1A2CYP2D6HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000702-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-06-19 US disclosed
US-9976088-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element having the same CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-9976085-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed
US-9644147-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2017-05-09 US disclosed
US-20170066969-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-03-09 US disclosed
US-20170029703-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THE SAME CHI MEI CORPORATION (TW) 2017-02-02 US disclosed
US-20170022419-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-01-26 US disclosed