SCHEMBL105316

SCHEMBL105316

CC1CCC(C2CCC(OC(=O)c3cc(N)cc(N)c3)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.49
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
HTR3E A5X5Y0 2/20 0.40
HTR3B O95264 2/20 0.40
HTR3A P46098 2/20 0.40
HTR3D Q70Z44 2/20 0.40
HTR3C Q8WXA8 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2C19 P33261 1/20 0.40
NR1I2 O75469 1/20 0.40
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
ST14 Q9Y5Y6 1/20 0.38
STS P08842 4/20 0.38
CYP19A1 P11511 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17720302 1.00 SERPINE1 (0.49) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL16425683 0.95 SERPINE1 (0.53) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL13415419 0.86 MEN1 (0.55) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL11996902 0.86 SERPINE1 (0.50) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL17722780 0.85 SERPINE1 (0.49) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL10017552 0.84 SERPINE1 (0.45) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL13909981 0.82 SERPINE1 (0.43) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL14828376 0.81 SERPINE1 (0.54) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL27794285 0.80 SERPINE1 (0.53) SERPINE1CYP1A2CYP2D6HTR3EHTR3B
SCHEMBL18409873 0.80 SERPINE1 (0.53) SERPINE1CYP1A2CYP2D6HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019189637-A1 NOVEL LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
US-10000702-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-06-19 US disclosed
US-9976085-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-9976088-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element having the same CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-9976088-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element having the same CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-9816032-B2 Liquid crystal alignment agent and uses thereof CHI MEI CORPORATION (TW) 2017-11-14 US disclosed
US-9816032-B2 Liquid crystal alignment agent and uses thereof CHI MEI CORPORATION (TW) 2017-11-14 US disclosed
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed
US-9644147-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2017-05-09 US disclosed
US-20170066969-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-03-09 US disclosed
US-20120101224-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2012-04-26 US disclosed
US-20120094015-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-04-19 US disclosed
US-20120058262-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-03-08 US disclosed
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-20 US disclosed
US-20110255042-A1 METHOD FOR MAKING A TREATED POLYMER FOR A LIQUID CRYSTAL ALIGNMENT AGENT, THE TREATED POLYMER MADE THEREBY, AND LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CONTAINING THE TREATED POLYMER CHI MEI CORPORATION (TW) 2011-10-20 US disclosed
US-20110082237-A1 Liquid crystal alignment agent, liquid crystal alignment film formed therefrom, and liquid crystal display element provided with the liquid crystal alignment film CHI-MEI CORPORATION 2011-04-07 US disclosed
US-20090280236-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2009-11-12 US disclosed
US-20090226640-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2009-09-10 US disclosed
US-7498068-B2 Liquid-crystal aligning agent, liquid-crystal alignment film comprising the same, and liquid-crystal element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-03 US disclosed
US-20070224370-A1 Liquid-Crystal Aligning Agent, Liquid-Crystal Alignment Film Comprising the Same, and Liquid-Crystal Element NISSAN CHEMICALS INDUSTRIES, LTD. (JP) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF PBRM1, PUF60, ALKBH1 SERPINE1 3574/4885CYP1A2 1798/4885CYP2D6 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.